Research highlights
January 15, 2024
Structures and mechanisms of SPARTA immune complexes published in Nucleic Acids Research!
Together with our collaborators Giada Finocchio and Martin Jinek, Bel, Ana, Clint and, Adrie resolved the structure and mechanisms underlying guide/target binding-mediated catalytic activation of SPARTA.
Read the (open access) article here.
April 28, 2022
The inaugural paper of the Swarts lab has been published in Cell!
In this paper, Bel and Ana (together with our collaborators) resolved the function and mechanisms of SPARTA systems (Short Prokaryotic Argonaute TIR-APAZ), and like the Spartans, it protects against invaders!
Read the press release here and find the (open access) article here.
The Swarts lab is embedded in the Laboratory of Biochemistry
at Wageningen University.
THE SWARTS LAB 