Have a look at the structures described in our studies here!
More structures following soon 🙂
Chroococcidiopsis thermalis pAgo (CtAgo) with bound ssDNA guide 3′ end
PDB: 9IAD (2.4Å)
Chroococcidiopsis thermalis Argonaute-associated Cas4 family enzyme (CtACE1)
PDB: 9IAB (1.57Å)
Microcystis aeruginosa Argonaute-associated Cas4 family enzyme (MaACE1)
PDB: 9IAC (2.52Å)
CryoEM structure of HrAgo1 in complex with a guide RNA
PDB: 8R3Z (3.4Å)
EMDB: EMD-18878
CryoEM structure of the apo BabSPARTA complex
PDB: 8QLO (2.57Å)
EMDB: EMD-18486
CryoEM structure of RNA/DNA bound BabSPARTA
PDB: 8QLP (3.09Å)
EMDB: EMD-18487
Mysterious protein A
Announced soon…
PDB: XXX (2.1Å)
Clostridium butyricum pAgo with ssDNA guide and target
PDB: 6QZK (3.5Å)
Francisella novicida Cas12a bound to crRNA and dsDNA
PDB: 6I1K (2.65Å)
Francisella novicida Cas12a bound to crRNA and ssDNA
PDB: 6I1L (3Å)
Francisella novicida Cas12a
bound to crRNA and dsDNA
PDB: 5NFV (2.5Å)
Francisella novicida Cas12a bound to a crRNA
PDB: 5NG6 (3.3Å)
THE SWARTS LAB 